Article
Identification of a novel interaction site between the large hepatitis delta antigen and clathrin that regulates the assembly of genotype III hepatitis delta virus.
Virology journal - 17 Oct 2022
Chiou Wei-Chung, Lu Hsu-Feng, Chen Jui-Chieh, Lai Yu-Heng, Chang Ming-Fu, Huang Yuan-Li, Tien Ni, Huang Cheng
Abstract excerpt
BACKGROUND: Hepatitis delta virus (HDV), a satellite virus of hepatitis B virus (HBV), is a small, defective RNA virus strongly associated with the most severe form of hepatitis and progressive chronic liver disease and cirrhosis. Chronic hepatitis D, resulting from HBV/HDV coinfection, is considered to be the most severe form of viral hepatitis and affects 12-20 million people worldwide. Involved in the...
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