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Structural biology of hepatitis C virus

1 Jan 2004

Abstract excerpt

Hepatitis C virus (HCV) causes acute and chronic liver disease in humans, including chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Studies of this virus have been hampered by the lack of a productive cell culture system; most information thus has been obtained from analysis of the HCV genome, heterologous expression systems, in vitro and in vivo models, and structural analyses. Structural analyses of...

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PMID: 14752815
DOI: 10.1002/hep.20032

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