Article
Genetic diversity in the transmission-blocking vaccine candidate Plasmodium vivax gametocyte protein Pvs230 from the China-Myanmar border area and central Myanmar.
Parasites & vectors - 17 Oct 2022
Zhao Xin, Hu Yubing, Zhao Yan, Wang Lin, Wu Zifang, Soe Myat Thu, Kyaw Myat Phone, Cui Liwang, Zhu Xiaotong, Cao Yaming
Abstract excerpt
BACKGROUND: Sexual stage surface antigens are potential targets of transmission-blocking vaccines (TBVs). The gametocyte and gamete surface antigen P230, a leading TBV candidate, is critical for red blood cell binding during exflagellation and subsequent oocyst development. Here, the genetic diversity of Pvs230 was studied in Plasmodium vivax parasite isolates from the China-Myanmar border (CMB) and central...
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