Article
A Secure High-Order Gene Interaction Detection Algorithm Based on Deep Neural Network.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Zhang Yongting, Gao Yonggang, Wang Huanhuan, Wu Huaming, Xia Youbing, Wu Xiang
Abstract excerpt
Identifying high-order Single Nucleotide Polymorphism (SNP) interactions of additive genetic model is crucial for detecting complex disease gene-type and predicting pathogenic genes of various disorders. We present a novel framework for high-order gene interactions detection, not directly identifying individual site, but based on Deep Learning (DL) method with Differential Privacy (DP), termed as Deep-DPGI....
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