Article
DL-ADR: a novel deep learning model for classifying genomic variants into adverse drug reactions.
BMC medical genomics - 10 Aug 2016
Liang Zhaohui, Huang Jimmy Xiangji, Zeng Xing, Zhang Gang
Abstract excerpt
BACKGROUND: Genomic variations are associated with the metabolism and the occurrence of adverse reactions of many therapeutic agents. The polymorphisms on over 2000 locations of cytochrome P450 enzymes (CYP) due to many factors such as ethnicity, mutations, and inheritance attribute to the diversity of response and side effects of various drugs. The associations of the single nucleotide polymorphisms (SNPs), the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
