Article
Mutation of the TP53 gene in acute lymphoblastic leukemia does not affect survival outcomes after haploidentical hematopoietic stem cell transplantation.
International journal of cancer - 1 Mar 2023
Zhou Cuiyan, Zheng Fengmei, Xu Lanping, Zhang Xiaohui, Chang Yingjun, Mo Xiaodong, Sun Yuqian, Huang Xiaojun, Wang Yu
Abstract excerpt
Previous studies have demonstrated that TP53 mutation is correlated with insufficient therapy response and unfavorable prognosis in acute lymphoblastic leukemia (ALL). Few studies have investigated the impact of TP53 mutation in ALL patients after haploidentical hematopoietic stem cell transplantation (haplo-HSCT). We completed a retrospective study of 65 ALL patients with available TP53 status who underwent...
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