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Drug toxicity assessment: cell proliferation versus cell death

14 Oct 2022

Abstract excerpt

Analysis of the toxicity of chemotherapeutic drugs is one of the main tasks of clinical pharmacology. Decreased viability of tumor cells may reflect two important physiological processes, namely the arrest of proliferation associated with disturbances in cellular metabolism or actual cell death. Elucidation of the exact processes mediating a reduction in the number of cells is fundamentally important to establish...

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PMID: 36241623
DOI: 10.1038/s41420-022-01207-x

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