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In Vitro Cell Death Discrimination and Screening Method by Simple and Cost-Effective Viability Analysis

1 Jan 2017

Abstract excerpt

BACKGROUND/AIMS: For in vitro cytotoxicity testing, discrimination of apoptosis and necrosis represents valuable information. Viability analysis performed at two different time points post treatment could serve such a purpose because the dynamics of metabolic activity of apoptotic and necrotic cells is different, i.e. a more rapid decline of cellular metabolism during necrosis whereas cellular metabolism is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28291963
DOI: 10.1159/000460910

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