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Article

Optimization of the base editor BE4max in chicken somatic cells.

Poultry science - 1 Dec 2022

Xu Tianpeng, Zhong Jing, Huang Zhenwen, Yu Lintian, Zheng Jitan, Xie Long, Sun Lingling, Liu Xingting, Lu Yangqing

Abstract excerpt

Advanced animal reproductive and breeding biotechnology has made it possible to alter traits or create new genetic resources by the direct knock-in or knock-out of target genes. Base editing technology can achieve single-base mutations without double-stranded DNA breaks, and is a promising tool for use in the genetic modification and breeding of livestock. However, the application of base editors (BEs) in chicken...

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Identifiers

PMID: 36240636
DOI: 10.1016/j.psj.2022.102174
PMCID: PMC9573927

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