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The Achilles’ heel of cancer survivors: fundamentals of accelerated cellular senescence

30 Jun 2022

Abstract excerpt

Recent improvements in cancer treatment have increased the lifespan of pediatric and adult cancer survivors. However, cancer treatments accelerate aging in survivors, which manifests clinically as the premature onset of chronic diseases, such as endocrinopathies, osteoporosis, cardiac dysfunction, subsequent cancers, and geriatric syndromes of frailty, among others. Therefore, cancer treatment-induced early aging...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35775492
DOI: 10.1172/jci158452

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