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Article

Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance.

Clinical pharmacology and therapeutics - 1 Dec 2002

Scordo Maria Gabriella, Pengo Vittorio, Spina Edoardo, Dahl Marja Liisa, Gusella Milena, Padrini Roberto

Abstract excerpt

OBJECTIVE: Our objective was to determine the influence of cytochrome P450 (CYP) 2C9 and CYP2C19 genetic polymorphisms on warfarin dose requirement and metabolic clearance. METHODS: The study population consisted of 93 Italian outpatients receiving long-term warfarin anticoagulant therapy (intern...

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Source

Identifiers

PMID: 12496751
DOI: 10.1067/mcp.2002.129321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12496751-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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