Article
APOL1 genotyping via buccal mucosa cell samples to establish risk of kidney disease.
BMC nephrology - 10 Oct 2022
Alladagbin Dona Jeanne, da Silva Carlos Gustavo Regis, Silva Luciano Kalabric, Dos-Santos Washington Lc, de Sá Oliveira Geraldo Gileno
Abstract excerpt
Two alleles (G1 and G2) of the apolipoprotein 1 gene (APOL1) predispose people of African descent to developing or accelerating the course of certain types of kidney disease. Population studies to determine the frequency of the G1 and G2 alleles are important to inform resource allocation by public health authorities. Traditionally, APOL1 genotyping is carried out in blood samples. However, sample collection,...
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