Article
Role of TGF-β1 +869T>C polymorphism in renal dysfunction one year after heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Dec 2022
López-Ibor Jorge V, Citores María J, Portoles Jose, Gómez-Bueno Manuel, Sánchez-Sobrino Beatriz, Muñoz Alejandro, Cuervas-Mons Valentín, Segovia-Cubero Javier
Abstract excerpt
BACKGROUND: Chronic kidney disease is a major complication after heart transplantation with wide inter-individual variability. Calcineurin inhibitor nephrotoxicity, mediated by transforming growth factor-beta1 (TGF-β1), is an important contributing factor. Our objective was to evaluate the association between TGF-β1 polymorphisms and renal dysfunction 1-year after heart transplantation. METHODS: Single-center...
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