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Article

Influence of TGFB1 and CTLA4 polymorphisms on calcineurin inhibitors dose and risk of acute rejection in renal transplantation.

Scientific reports - 2 Sept 2021

Bogacz Anna, Wolek Marlena, Sieńko Jerzy, Czerny Bogusław, Machaliński Bogusław, Olbromski Piotr, Kotowski Maciej

Abstract excerpt

Organ transplant is often the treatment of choice as it extends and improves patient life. Immunosuppressive treatment, which prevents acute rejection of the organ, is used in transplant patients to prevent the loss of transplant. The aim of the study was to determine the impact of the CTLA4 (+49A>G, rs231775) and the TGF-β1 (-800G>A, rs1800468) polymorphisms on the therapeutic effect of immunosuppressive drugs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34475433
DOI: 10.1038/s41598-021-96457-7
PMCID: PMC8413317

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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