Article
Recipient RAS gene variants and renal allograft function.
Transplantation - 27 Mar 2002
Nicod Jérôme, Richard Alain, Frey Felix J, Ferrari Paolo
Abstract excerpt
BACKGROUND: Genetic variants of the renin-angiotensin system (RAS) have been implicated in the progression of native kidney diseases. A decreased long-term renal allograft function has also been associated with increased activity of RAS, which may be genetically determined. METHODS: The effect of the angiotensinogen (AGT), angiotensin-converting enzyme (ACE), angiotensin type 1 receptor (AGT1R), and aldosterone...
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