Article
Iron status and the risk of sepsis and severe COVID-19: a two-sample Mendelian randomization study.
Scientific reports - 28 Sept 2022
Mohus Randi Marie, Flatby Helene, Liyanarachi Kristin V, DeWan Andrew T, Solligård Erik, Damås Jan Kristian, Åsvold Bjørn Olav, Gustad Lise T, Rogne Tormod
Abstract excerpt
Observational studies have indicated an association between iron status and risk of sepsis and COVID-19. We estimated the effect of genetically-predicted iron biomarkers on risk of sepsis and risk of being hospitalized with COVID-19, performing a two-sample Mendelian randomization study. For risk of sepsis, one standard deviation increase in genetically-predicted serum iron was associated with odds ratio (OR) of...
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