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Article

A statistical network pre-processing method to improve relevance and significance of gene lists in microarray gene expression studies.

BMC bioinformatics - 27 Sept 2022

Agapito Giuseppe, Milano Marianna, Cannataro Mario

Abstract excerpt

BACKGROUND: Microarrays can perform large scale studies of differential expressed gene (DEGs) and even single nucleotide polymorphisms (SNPs), thereby screening thousands of genes for single experiment simultaneously. However, DEGs and SNPs are still just as enigmatic as the first sequence of the genome. Because they are independent from the affected biological context. Pathway enrichment analysis (PEA) can...

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Identifiers

PMID: 36167506
DOI: 10.1186/s12859-022-04936-z
PMCID: PMC9516794

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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