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Article

Effects of human induced pluripotent stem cell-derived intestinal organoids on colitis-model mice

9 Sept 2022

Abstract excerpt

Introduction Ulcerative colitis (UC) is an inflammatory bowel disease characterized by repeated remissions and relapses. Immunosuppressive drugs have facilitated the induction and maintenance of remission in many patients with UC. However, immunosuppressive drugs cannot directly repair impaired intestinal mucosa and are insufficient for preventing relapse. Therefore, new treatment approaches to repair the damaged...

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PMID: 36161099
DOI: 10.1016/j.reth.2022.08.004

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