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Article

Targeting mitochondrial tyrosyl-tRNA synthetase YARS2 suppresses colorectal cancer progression.

Cancer biology & therapy - 31 Dec 2022

Fang Qingxia, Lin Jingyang, Gao Liang, Pan Ruolang, Zheng Xiaochun

Abstract excerpt

Defects in tRNA expressions and modifications had been linked to various types of tumorigenesis and progression in recent studies, including colorectal cancer. In the present study, we evaluated transcript levels of mitochondrial tyrosyl-tRNA synthetase YARS2 in both colorectal cancer tissues and normal colorectal tissues using qRT-PCR. The results revealed that the mRNA expression level of YARS2 in colorectal...

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Identifiers

PMID: 36154909
DOI: 10.1080/15384047.2022.2127603
PMCID: PMC9518999

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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