Article
Association of aminoacyl-tRNA synthetases with cancer.
Topics in current chemistry - 1 Jan 2014
Kim Doyeun, Kwon Nam Hoon, Kim Sunghoon
Abstract excerpt
Although aminoacyl-tRNA synthetases (ARSs) and ARS-interacting multi-functional proteins (AIMPs) have long been recognized as housekeeping proteins, evidence indicating that they play a key role in regulating cancer is now accumulating. In this chapter we will review the conventional and non-conventional functions of ARSs and AIMPs with respect to carcinogenesis. First, we will address how ARSs and AIMPs are...
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