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Article

SHMT2 Drives the Progression of Colorectal Cancer by Regulating UHRF1 Expression

15 Feb 2022

Abstract excerpt

Introduction. Serine hydroxymethyltransferase 2 (SHMT2) has a critical role in serine-glycine metabolism to drive cancer cell proliferation. Yet, the function of SHMT2 in tumorigenesis, especially in human colorectal cancer (CRC) progression, remains largely unclear. Materials and Methods. CRC and paired normal samples were collected in the Department of Colorectal Surgery, Xinhua Hospital, Shanghai Jiao Tong...

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PMID: 35211429
DOI: 10.1155/2022/3758697

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