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Article

Innate frequency-discrimination hyperacuity in Williams-Beuren syndrome mice.

Cell - 13 Oct 2022

Davenport Christopher M, Teubner Brett J W, Han Seung Baek, Patton Mary H, Eom Tae-Yeon, Garic Dusan, Lansdell Benjamin J, Shirinifard Abbas, Chang Ti-Cheng, Klein Jonathon, Pruett-Miller Shondra M, Blundon Jay A, Zakharenko Stanislav S

Abstract excerpt

Williams-Beuren syndrome (WBS) is a rare disorder caused by hemizygous microdeletion of ∼27 contiguous genes. Despite neurodevelopmental and cognitive deficits, individuals with WBS have spared or enhanced musical and auditory abilities, potentially offering an insight into the genetic basis of auditory perception. Here, we report that the mouse models of WBS have innately enhanced frequency-discrimination acuity...

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Identifiers

PMID: 36152627
DOI: 10.1016/j.cell.2022.08.022
PMCID: PMC9588278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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