Article

Increased Potency and Breadth of SARS-CoV-2 Neutralizing Antibodies After a Third mRNA Vaccine Dose

2022-02-15

Abstract excerpt

The omicron variant of SARS-CoV-2 infected very large numbers of SARS-CoV-2 vaccinated and convalescent individuals 1–3 . The penetrance of this variant in the antigen experienced human population can be explained in part by the relatively low levels of plasma neutralizing activity against Omicron in people who were infected or vaccinated with the original Wuhan-Hu-1 strain 4–7 . The 3 rd mRNA vaccine dose prod...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: aed2290b-e849-5b9a-b97a-f1aa38411c8e
DOI: 10.1101/2022.02.14.480394

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Increased Potency and Breadth of SARS-CoV-2 Neutralizing Antibodies After a Third mRNA Vaccine DoseDOI 10.1101/2022.02.14.480394Read

Increased memory B cell potency and breadth after a SARS-CoV-2 mRNA boostSemantic proximity Read

A subset of Memory B-derived antibody repertoire from 3-dose vaccinees is ultrapotent against diverse and highly transmissible SARS-CoV-2 variants, including OmicronSemantic proximity Read

SARS-CoV-2 Omicron Variant Infection of Individuals with High Titer Neutralizing Antibodies Post-3<sup>rd</sup> mRNA Vaccine DoseSemantic proximity Read

An ancestral SARS-CoV-2 vaccine induces anti-Omicron variants antibodies by hypermutationSemantic proximity Read

Rapid Decline in Vaccine-Boosted Neutralizing Antibodies Against SARS-CoV-2 Omicron VariantSemantic proximity Read

Four doses of the inactivated SARS-CoV-2 vaccine redistribute humoral immune responses away from the Receptor Binding DomainSemantic proximity Read

An ancestral SARS-CoV-2 vaccine induces anti-Omicron variants antibodies by hypermutationSemantic proximity Read

mRNA-Based COVID-19 Vaccine Boosters Induce Neutralizing Immunity Against SARS-CoV-2 Omicron VariantSemantic proximity Read

Plasma neutralization properties of the SARS-CoV-2 Omicron variantSemantic proximity Read

Antigen presentation dynamics shape the response to emergent variants like SARS-CoV-2 Omicron strain after multiple vaccinations with wild type strainSemantic proximity Read

mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variantSemantic proximity Read

Omicron: Call for updated vaccinesSemantic proximity Read