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Increased memory B cell potency and breadth after a SARS-CoV-2 mRNA boost

21 Apr 2022

Abstract excerpt

Abstract The Omicron variant of SARS-CoV-2 infected many vaccinated and convalescent individuals 1–3 . Despite the reduced protection from infection, individuals who received three doses of an mRNA vaccine were highly protected from more serious consequences of infection 4 . Here we examine the memory B cell repertoire in a longitudinal cohort of individuals receiving three mRNA vaccine doses 5,6 . We find that...

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PMID: 35447027
DOI: 10.1038/s41586-022-04778-y

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