Article

SARS-CoV-2 Neutralizing Antibodies After Bivalent vs. Monovalent Booster

2023-02-14

Abstract excerpt

Bivalent mRNA vaccine boosters expressing Omicron BA.5 spike and ancestral D614G spike were introduced to attempt to boost waning antibody titers and broaden coverage against emerging SARS-CoV-2 lineages. Previous reports showed that peak serum neutralizing antibody (NAb) titers against SARS-CoV-2 variants following bivalent booster were similar to peak titers following monovalent booster. It remains unknown wheth...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 77d6caea-f94f-5714-87fe-1fca84d1c2fe
DOI: 10.1101/2023.02.13.528341

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 Neutralizing Antibodies After Bivalent vs. Monovalent BoosterDOI 10.1101/2023.02.13.528341Read

Antibody responses to Omicron BA.4/BA.5 bivalent mRNA vaccine booster shotSemantic proximity Read

Deep immunological imprinting due to the ancestral spike in the current bivalent COVID-19 vaccineSemantic proximity Read

Low neutralization of SARS-CoV-2 Omicron BA.2.75.2, BQ.1.1, and XBB.1 by 4 doses of parental mRNA vaccine or a BA.5-bivalent boosterSemantic proximity Read

Exposure to BA.4/BA.5 Spike glycoprotein drives pan-Omicron neutralization in vaccine-experienced humans and miceSemantic proximity Read

Recall of pre-existing cross-reactive B cell memory following Omicron breakthrough infectionSemantic proximity Read

Exposure to BA.4/5 S protein drives neutralization of Omicron BA.1, BA.2, BA.2.12.1, and BA.4/5 in vaccine-experienced humans and miceSemantic proximity Read

Recall of preexisting cross-reactive B cell memory after Omicron BA.1 breakthrough infectionSemantic proximity Read

Deep immunological imprinting due to the ancestral spike in the current bivalent COVID-19 vaccineSemantic proximity Read

Evaluation of bivalent Omicron BA.1 booster vaccination after different priming regimens in healthcare workers (SWITCH ON): a randomized controlled trialSemantic proximity Read

Bivalent Omicron BA.1 vaccine booster increases memory B cell breadth and neutralising antibodies against emerging SARS-CoV-2 variantsSemantic proximity Read

Characterizing SARS-CoV-2 neutralization profiles after bivalent boosting using antigenic cartographySemantic proximity Read

Antigenic sin of wild-type SARS-CoV-2 vaccine shapes poor cross-neutralization of BA.4/5/2.75 subvariants in BA.2 breakthrough infectionsSemantic proximity Read