Article
Breast cancer polygenic risk scores are associated with short-term risk of poor prognosis breast cancer.
Breast cancer research and treatment - 1 Nov 2022
McCarthy Anne Marie, Manning Alisa K, Hsu Sarah, Welch Michaela, Moy Beverly, Lehman Constance D, Armstrong Katrina
Abstract excerpt
PURPOSE: Polygenic risk scores (PRS) for breast cancer may help guide screening decisions. However, few studies have examined whether PRS are associated with risk of short-term or poor prognosis breast cancers. The study purpose was to evaluate the association of the 313 SNP breast cancer PRS with 2-year risk of poor prognosis breast cancer. METHODS: We evaluated the association of breast cancer PRS with breast...
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