Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

d-StructMAn: Containerized structural annotation on the scale from genetic variants to whole proteomes.

GigaScience - 20 Sept 2022

Gress Alexander, Srikakulam Sanjay K, Keller Sebastian, Ramensky Vasily, Kalinina Olga V

Abstract excerpt

BACKGROUND: Structural annotation of genetic variants in the context of intermolecular interactions and protein stability can shed light onto mechanisms of disease-related phenotypes. Three-dimensional structures of related proteins in complexes with other proteins, nucleic acids, or ligands enrich such functional interpretation, since intermolecular interactions are well conserved in evolution. RESULTS: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acids
Share to Genetic Variation
Share to Molecular Sequence Annotation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nucleic Acids

Share to Nucleotides

Share to Proteome

Source

Open in PubMed Open full text

Identifiers

PMID: 36130085
DOI: 10.1093/gigascience/giac086
PMCID: PMC9487898

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

d-StructMAn: Containerized structural annotation on the scale from genetic variants to whole proteomes.PMID 36130085Read ↗

Robust Classification of Protein Variation Using Structural Modeling and Large-Scale Data IntegrationSemantic proximity Read ↗

StructMAn: annotation of single-nucleotide polymorphisms in the structural context.Semantic proximity Read ↗

Robust classification of protein variation using structural modelling and large-scale data integration.Semantic proximity Read ↗

Genomics 2 Proteins portal: A resource and discovery tool for linking genetic screening outputs to protein sequences and structuresSemantic proximity Read ↗

mutation3D: Cancer Gene Prediction Through Atomic Clustering of Coding Variants in the Structural Proteome.Semantic proximity Read ↗

Genomics 2 Proteins portal: a resource and discovery tool for linking genetic screening outputs to protein sequences and structures.Semantic proximity Read ↗

GeniePool 2.0: advancing variant analysis through CHM13-T2T, AlphaMissense, gnomAD V4 integration, and variant co-occurrence queries.Semantic proximity Read ↗

DeltaMut: An Integrative Database of AlphaFold2-Derived Missense Variant StructuresSemantic proximity Read ↗

Systematic assessment of structural variant annotation tools for genomic interpretation.Semantic proximity Read ↗

MetaDome: Pathogenicity analysis of genetic variants through aggregation of homologous human protein domainsSemantic proximity Read ↗

MSV3d: database of human MisSense Variants mapped to 3D protein structure.Semantic proximity Read ↗

A structure-aware framework for genomic variant interpretation in genetic skeletal disordersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.