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Article

Apolipoprotein E mediates cell resistance to influenza virus infection

21 Sept 2022

Abstract excerpt

Viruses exploit host cell machinery to support their replication. Defining the cellular proteins and processes required for a virus during infection is crucial to understanding the mechanisms of virally induced disease and designing host-directed therapeutics. Here, we perform a genome-wide CRISPR-Cas9–based screening in lung epithelial cells infected with the PR/8/NS1-GFP virus and use GFP hi cell as a unique...

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PMID: 36129973
DOI: 10.1126/sciadv.abm6668

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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