Article
Pyrazinamide resistance in rifampicin discordant tuberculosis.
PloS one - 1 Jan 2022
Mvelase Nomonde Ritta, Singh Ravesh, Swe Swe-Han Khine, Mlisana Koleka Patience
Abstract excerpt
INTRODUCTION: Mycobacterium tuberculosis strains with phenotypically susceptible rpoB mutations (rifampicin discordant) have emerged following implementation of rapid molecular drug resistance testing for tuberculosis. Whilst rifampicin resistance is known to be associated with resistance to other rifamycins (rifapentine and rifabutin) as well as isoniazid and pyrazinamide, rifampicin discordant strains have...
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