Article
Combining Phenotypes of Nucleotide Excision Repair Pathway to Predict the Risk of Head and Neck Squamous Cell Carcinomas in a Chinese Population.
Disease markers - 1 Jan 2022
Liang Yiqian, Zhang Ling, Chen Zichen, Chen Jiayu, Fang Sui, Zhang Ting, Zhu Yun, Liu Jie, Li Baiya, Shao Yuan, Xing Juanli, Zhang Shaoqiang, Han Peng
Abstract excerpt
Background: Nucleotide excision repair (NER) is pivotal in the development of smoking-related malignancies. Nine core genes (XPA, XPB, XPC, XPD, XPF, XPG, ERCC1, DDB1, and DDB2) are highly involved in the NER process. We combined two phenotypes of NER pathway (NER protein and NER gene mRNA expression) and evaluated their associations with the risks of the head and neck squamous cell carcinomas (HNSCCs) in a...
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