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Article

Reduced mRNA expression of nucleotide excision repair genes in lymphocytes and risk of squamous cell carcinoma of the head and neck.

Carcinogenesis - 1 May 2017

Han Peng, Gao Fengqin, Liu Hongliang, Liu Zhensheng, Shi Qiong, Troy Jesse D, Owzar Kouros, Lee Walter, Zevallos Jose P, Sturgis Erich M, Wei Qingyi

Abstract excerpt

Nucleotide excision repair (NER) plays a critical role in the development of smoking-related cancers. We hypothesize that mRNA expression levels of NER genes are associated with risk of the squamous cell carcinoma of head and neck (SCCHN). To test this hypothesis, we conducted a case-control study of 260 SCCHN patients and 246 cancer-free controls by measuring the mRNA expression levels of eight core NER genes in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Squamous Cell Carcinoma of Head and Neck

Source

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Identifiers

PMID: 28379545
DOI: 10.1093/carcin/bgx028
PMCID: PMC5461936

Genes

DDB1
ERCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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