Article
Sex differences in susceptibility to influenza A virus infection depend on host genotype.
PloS one - 1 Jan 2022
Sabikunnahar Bristy, Lahue Karolyn G, Asarian Loredana, Fang Qian, McGill Mahalia M, Haynes Laura, Teuscher Cory, Krementsov Dimitry N
Abstract excerpt
Infection with the respiratory pathogen influenza A virus (IAV) causes significant morbidity and mortality each year. While host genotype is thought to contribute to severity of disease, naturally occurring genetic determinants remain mostly unknown. Moreover, more severe disease is seen in women compared with men, but genetic mechanisms underlying this sex difference remain obscure. Here, using IAV infection in...
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