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Article

Genetic variations and haplotype structures of the glutathione S-transferase genes, GSTT1 and GSTM1, in a Japanese patient population.

Drug metabolism and pharmacokinetics - 1 Jan 2009

Tatewaki Naoko, Maekawa Keiko, Katori Noriko, Kurose Kouichi, Kaniwa Nahoko, Yamamoto Noboru, Kunitoh Hideo, Ohe Yuichiro, Nokihara Hiroshi, Sekine Ikuo, Tamura Tomohide, Yoshida Teruhiko, Saijo Nagahiro, Saito Yoshiro, Sawada Jun-ichi

Abstract excerpt

Glutathione S-transferases (GSTs) play a vital role in phase II biotransformation of many synthetic chemicals including anticancer drugs. Deletion polymorphisms in GSTT1 and GSTM1 are reportedly associated, albeit controversial, with an increased risk in cancer as well as with altered responses t...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19252342
DOI: 10.2133/dmpk.24.118

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19252342-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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