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Induction of functional xeno-free MSCs from human iPSCs via a neural crest cell lineage

15 Sept 2022

Abstract excerpt

Mesenchymal stem/stromal cells (MSCs) are adult multipotent stem cells. Here, we induced MSCs from human induced pluripotent stem cells (iPSCs) via a neural crest cell (NCC) lineage under xeno-free conditions and evaluated their in vivo functions. We modified a previous MSC induction method to work under xeno-free conditions. Bovine serum albumin-containing NCC induction medium and fetal bovine serum-containing...

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PMID: 36109564
DOI: 10.1038/s41536-022-00241-8

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