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Generation of clinical-grade human induced pluripotent stem cells in Xeno-free conditions

12 Nov 2015

Abstract excerpt

INTRODUCTION: Human induced pluripotent stem cells (hiPSCs) are considered as one of the most promising seed cell sources in regenerative medicine. Now hiPSC-based clinical trials are underway. To ensure clinical safety, cells used in clinical trials or therapies should be generated under GMP conditions, and with Xeno-free culture media to avoid possible side effects like immune rejection that induced by the Xeno...

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PMID: 26564165
DOI: 10.1186/s13287-015-0206-y

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