Article
Molecular annotation of extramedullary acute myeloid leukemia identifies high prevalence of targetable mutations.
Cancer - 1 Nov 2022
Ball Somedeb, Knepper Todd C, Deutsch Yehuda E, Samra Wassim, Watts Justin M, Bradley Terrence J, Chan Onyee, Hussaini Mohammad Omar, Zhang Ling, Sweet Kendra L, Kuykendall Andrew T, Talati Chetasi, Padron Eric, Komrokji Rami S, Lancet Jeffrey E, Sallman David A
Abstract excerpt
BACKGROUND: Genomic landscape of extramedullary acute myeloid leukemia (EM-AML), including myeloid sarcoma (MS) and leukemia cutis (LC), is not well characterized. The potential utility of next-generation sequencing (NGS) using EM tissue is not established. METHODS: In this multicenter retrospective study, clinical and NGS data were collected on patients with EM-AML. All statistical analyses were performed in...
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