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Article

Population Pharmacokinetic Modeling of Bedaquiline among Multidrug-Resistant Pulmonary Tuberculosis Patients from China.

Antimicrobial agents and chemotherapy - 18 Oct 2022

Zou Jin, Chen Shuyan, Rao Weiqiao, Fu Liang, Zhang Jiancong, Liao Yunli, Zhang Ying, Lv Ning, Deng Guofang, Yang Shijin, Lin Liang, Li Lujin, Liu Siqi, Qu Jiuxin

Abstract excerpt

Bedaquiline has been widely used as a part of combination dosage regimens for the treatment of multidrug-resistant tuberculosis (MDR-TB) patients with limited options. Although the effectiveness and safety of bedaquiline have been demonstrated in clinical trials, limited studies have investigated the significant pharmacokinetics and the impact of genotype on bedaquiline disposition. Here, we developed a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36106884
DOI: 10.1128/aac.00811-22
PMCID: PMC9578397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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