Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The utility of sputum supernatant as an alternative liquid biopsy specimen for next-generation sequencing-based somatic variation profiling

1 Apr 2022

Abstract excerpt

Background: Comprehensive genomic profiling has become standard clinical practice in the management of advanced lung cancer. In addition to tissue and plasma, other body fluids are also being actively explored as alternative sources of tumor DNA. This study investigated the utility of induced sputum obtained from patients with non-small-cell lung cancer (NSCLC) for somatic variation profiling. Methods: Our study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Lung Cancer Diagnosis and Treatment
Share to Lung Cancer Treatments and Mutations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35571392
DOI: 10.21037/atm-22-1297

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The utility of sputum supernatant as an alternative liquid biopsy specimen for next-generation sequencing-based somatic variation profilingPMID 35571392Read ↗

The utility of sputum supernatant as an alternative liquid biopsy specimen for next-generation sequencing-based genomic profilingSemantic proximity Read ↗

Comprehensive characterization reveals sputum supernatant as a valuable alternative liquid biopsy for genome profiling in advanced non-small cell lung cancerSemantic proximity Read ↗

Differences in the genomic profiles of cell‐free DNA between plasma, sputum, urine, and tumor tissue in advanced NSCLCSemantic proximity Read ↗

Malignant pleural effusion supernatant is an alternative liquid biopsy specimen for comprehensive mutational profilingSemantic proximity Read ↗

Feasibility of Bronchial Washing Fluid-Based Approach to Early-Stage Lung Cancer DiagnosisSemantic proximity Read ↗

Comparative analysis of genomic profiles between tissue-based and plasma-based next-generation sequencing in patients with non-small cell lung cancer.Semantic proximity Read ↗

Sputum cell-free DNA for detection of alterations of multiple driver genes in lung adenocarcinoma.Semantic proximity Read ↗

Plasma biopsy by Tag-sequencing: an acceptable alternative to tumor tissue profiling in non-small-cell lung cancer.Semantic proximity Read ↗

Study on NGS-based molecular profiling of malignant pleural effusion supernatant cfDNA in guiding targeted therapy for non-small cell lung cancer.Semantic proximity Read ↗

Tumor-derived DNA from pleural effusion supernatant as a promising alternative to tumor tissue in genomic profiling of advanced lung cancerSemantic proximity Read ↗

Detection of EGFR gene mutation status from pleural effusions and other body fluid specimens in patients with lung adenocarcinomaSemantic proximity Read ↗

Distinct profile of cell-free DNA in malignant pleural effusion of non-small cell lung cancer and its impact on clinical genetic testing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.