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Advances on the roles of tenascin-C in cancer

14 Sept 2022

Abstract excerpt

The roles of the extracellular matrix molecule tenascin-C (TNC) in health and disease have been extensively reviewed since its discovery over 40 years ago. Here, we will describe recent insights into the roles of TNC in tumorigenesis, angiogenesis, immunity and metastasis. In addition to high levels of expression in tumors, and during chronic inflammation, and bacterial and viral infection, TNC is also expressed...

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PMID: 36102918
DOI: 10.1242/jcs.260244

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