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Beyond the Norm: The emerging interplay of complement system and extracellular matrix in the tumor microenvironment

9 Jan 2025

Abstract excerpt

Ground-breaking awareness has been reached about the intricate and dynamic connection between developing tumors and the host immune system. Being a powerful arm of innate immunity and a functional bridge with adaptive immunity, the complement system (C) has also emerged as a pivotal player in the tumor microenvironment (TME). Its "double-edged sword" role in cancer can find an explanation in the controversial...

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PMID: 39793258
DOI: 10.1016/j.smim.2025.101929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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