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Biology of Tenascin C and its Role in Physiology and Pathology

6 Apr 2023

Abstract excerpt

Tenascin-C (TNC) is a multimodular extracellular matrix (ECM) protein hexameric with several molecular forms (180-250 kDa) produced by alternative splicing at the pre-mRNA level and protein modifications. The molecular phylogeny indicates that the amino acid sequence of TNC is a well-conserved protein among vertebrates. TNC has binding partners, including fibronectin, collagen, fibrillin-2, periostin,...

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PMID: 37021423
DOI: 10.2174/0929867330666230404124229

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