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Antiviral resistance testing for DNA viruses in immunocompromised patients: Mechanisms, clinical utility, and limitations.

Diagnostic microbiology and infectious disease - 1 Nov 2026

Hijano Diego R, Gu Linlin, Liu Benjamin M, Cherian Sree Sarah, Dale Suzanne E, Starolis Meghan W

Abstract excerpt

Immunocompromised patients, including transplant recipients, individuals receiving chemotherapy or chronic immunosuppression, and those with primary or acquired immunodeficiency, are at increased risk for severe viral infections and treatment failure due to antiviral drug resistance (ADR). In these populations, prolonged viral replication under antiviral pressure promotes the emergence of resistance-associated...

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PMID: 42284771
DOI: 10.1016/j.diagmicrobio.2026.117492

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