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Erythroblastic islands: niches for erythropoiesis

23 Jul 2008

Abstract excerpt

Erythroblastic islands, the specialized niches in which erythroid precursors proliferate, differentiate, and enucleate, were first described 50 years ago by analysis of transmission electron micrographs of bone marrow. These hematopoietic subcompartments are composed of erythroblasts surrounding a central macrophage. A hiatus of several decades followed, during which the importance of erythroblastic islands...

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PMID: 18650462
DOI: 10.1182/blood-2008-03-077883

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