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Article

[Somatic mutations and longevity].

Medecine sciences : M/S - 1 Jan 2000

Jordan Bertrand

Abstract excerpt

New approaches allow precise measurement of somatic mutations in tissues. Applied to a diverse set of mammals, these methods show that somatic mutation load increases with age (as expected) but reaches similar levels near the end of life for animals with extremely different longevity. This is an important result that has many repercussions on concepts of aging and of evolution of longevity.

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Identifiers

PMID: 36094245
DOI: 10.1051/medsci/2022098

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