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Article

Lactate: A regulator of immune microenvironment and a clinical prognosis indicator in colorectal cancer

26 Aug 2022

Abstract excerpt

Lactate can play an immunosuppressive role in the tumor microenvironment and promote tumor development by recruiting and inducing the activity of immunosuppressive cells and molecules. High lactate concentrations are important for tumor cell metastasis, angiogenesis, and treatment resistance. With the in-depth studies on tumor metabolism, lactate, one of the key factors involved in glycolysis, has been increasing...

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PMID: 36091047
DOI: 10.3389/fimmu.2022.876195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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