Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of Lactate-Related Gene Signature for Prediction of Progression and Immunotherapeutic Response in Skin Cutaneous Melanoma

21 Feb 2022

Abstract excerpt

Skin cutaneous melanoma (SKCM) is a skin cancer type characterized by a high degree of immune cell infiltration. The potential function of lactate, a main metabolic product in the tumor microenvironment (TME) of SKCM, remains unclear. In this study, we systemically analyzed the predictive value of lactate-related genes (LRGs) for prognosis and response to immune checkpoint inhibitors (ICIs) in SKCM patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Ferroptosis and cancer prognosis
Share to Immune cells in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35265521
DOI: 10.3389/fonc.2022.818868

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of Lactate-Related Gene Signature for Prediction of Progression and Immunotherapeutic Response in Skin Cutaneous MelanomaPMID 35265521Read ↗

Unravelling the metabolic landscape of cutaneous melanoma: Insights from single-cell sequencing analysis and machine learning for prognostic assessment of lactate metabolism.Semantic proximity Read ↗

Identification of lactylation gene CALML5 and its correlated lncRNAs in cutaneous melanoma by machine learningSemantic proximity Read ↗

A novel lactate metabolism-related signature predicts prognosis and tumor immune microenvironment of breast cancerSemantic proximity Read ↗

A Lactate-related LncRNA Model for Predicting Prognosis, Immune Landscape and Therapeutic Response in Breast CancerSemantic proximity Read ↗

Lactate: A regulator of immune microenvironment and a clinical prognosis indicator in colorectal cancerSemantic proximity Read ↗

A glycolysis-related lncRNAs signature for predicting prognosis and evaluating the tumor immune microenvironment of cutaneous melanomaSemantic proximity Read ↗

Lactate score classification of hepatocellular carcinoma helps identify patients with tumors that respond to immune checkpoint blockade therapySemantic proximity Read ↗

Ferroptosis-Related lncRNA Signature Predicts Prognosis and Immunotherapy Efficacy in Cutaneous MelanomaSemantic proximity Read ↗

Ferroptosis-related lncRNA signature predicts prognosis and immunotherapy efficacy in cutaneous melanomaSemantic proximity Read ↗

Immuno-Genomic Landscape of Cutaneous Melanoma Identifies a Prognostic and Immunotherapeutically Relevant Gene SignatureSemantic proximity Read ↗

Characterization of Lactate Metabolism Score in Breast and Thyroid Cancers to Assist Immunotherapy via Large-Scale Transcriptomic Data AnalysisSemantic proximity Read ↗

Identification of Biomarkers with Therapeutic And prognostic Value in Skin Cutaneous MelanomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.