Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel hypoxia- and lactate metabolism-related molecular subtyping and prognostic signature for colorectal cancer

20 Jun 2024

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is a serious global health burden because of its high morbidity and mortality rates. Hypoxia and massive lactate production are hallmarks of the CRC microenvironment. However, the effects of hypoxia and lactate metabolism on CRC have not been fully elucidated. This study aimed to develop a novel molecular subtyping based on hypoxia-related genes (HRGs) and lactate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Cancer Immunotherapy and Biomarkers
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38902737
DOI: 10.1186/s12967-024-05391-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel hypoxia- and lactate metabolism-related molecular subtyping and prognostic signature for colorectal cancerPMID 38902737Read ↗

Development of lactate-related gene signature and prediction of overall survival and chemosensitivity in patients with colorectal cancer.Semantic proximity Read ↗

Hypoxia-related Genes as Prognostic Signature to Predict Prognosis and Immune Microenvironment of Colorectal Cancer PatientsSemantic proximity Read ↗

Development of a novel hypoxia-immune–related LncRNA risk signature for predicting the prognosis and immunotherapy response of colorectal cancerSemantic proximity Read ↗

Lactate: A regulator of immune microenvironment and a clinical prognosis indicator in colorectal cancerSemantic proximity Read ↗

Identification of a hypoxia-related gene prognostic signature in colorectal cancer based on bulk and single-cell RNA-seqSemantic proximity Read ↗

Machine learning-based glycolysis-associated molecular classification reveals differences in prognosis, TME, and immunotherapy for colorectal cancer patientsSemantic proximity Read ↗

Identification of a glycolysis- and lactate-related gene signature for predicting prognosis, immune microenvironment, and drug candidates in colon adenocarcinomaSemantic proximity Read ↗

Identification of a Hypoxia-Related LncRNA Signature for the Prognosis of Colorectal CancerSemantic proximity Read ↗

Effects of Hypoxia in Intestinal Tumors on Immune Cell Behavior in the Tumor MicroenvironmentSemantic proximity Read ↗

Effects of Hypoxia in Intestinal Tumors on Immune Cell Behavior in the Tumor MicroenvironmentSemantic proximity Read ↗

A Novel Lactate Metabolism-Related Gene Signature for Predicting Clinical Outcome and Tumor Microenvironment in Hepatocellular CarcinomaSemantic proximity Read ↗

A hypoxia–glycolysis–lactate-related gene signature for prognosis prediction in hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.