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Article

P130cas-FAK interaction is essential for YAP-mediated radioresistance of non-small cell lung cancer

10 Sept 2022

Abstract excerpt

Based on the RNA-sequencing data, previous studies revealed that extracellular matrix receptor interaction and focal adhesion signaling pathways were enriched in radioresistant non-small cell lung cancer (NSCLC) cell lines. As the principal members of these signaling pathways, recent studies showed that FAK controlled YAP's nuclear translocation and activation in response to mechanical activation. However, the...

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PMID: 36088346
DOI: 10.1038/s41419-022-05224-7

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