Article
Association of Paraoxonase-1 Genotype and Phenotype with Angiogram Positive Coronary Artery Disease.
Arquivos brasileiros de cardiologia - 1 Oct 2022
Soflaei Sara Saffar, Baktashian Mojtaba, Moghaddam Kiana Hosseinpour, Saberi-Karimian Maryam, Kosari Negin, Hashemi Seyed Mohammad, Mouhebati Mohsen, Amini Mahsa, Dehghani Mashallah, Esmaily Habibollah, Ebrahimi Mahmoud, Falsoleiman Homa, Nosrati-Tirkani Abolfazl, Sadabadi Fatemeh, Ferns Gordon A, Salehi Mansoor, Pasdar Alireza, Ghayour-Mobarhan Majid
Abstract excerpt
BACKGROUND: It has been shown that increased serum PON1 levels are protective against several disorders. Several single nucleotide polymorphisms (SNPs) of the PON1 gene have been reported to be associated with serum enzyme protein levels and activity. OBJECTIVE: To investigate the association of SNPs of PON1 and serum paraoxonase activity with coronary artery disease (CAD). METHODS: A total of 601 unrelated...
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