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Article

Paraoxonase 1 polymorphisms and ischemic stroke risk: A systematic review and meta-analysis.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Oct 2010

Dahabreh Issa J, Kitsios Georgios D, Kent David M, Trikalinos Thomas A

Abstract excerpt

PURPOSE: Paraoxonase 1 (PON1) polymorphisms have been implicated as risk factors for coronary artery disease, but the results of genetic association studies on the related phenotype of ischemic stroke are inconclusive. We performed a meta-analysis of published studies investigating the association between ischemic stroke and two nonsynonymous PON1 polymorphisms, rs662 (p.Q192R) and rs854560 (p.L55M) in humans....

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Source

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Identifiers

PMID: 20856122
DOI: 10.1097/GIM.0b013e3181ee81c6
PMCID: PMC3081717

Genes

PON1

Variants

rs854560

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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